Yellow sputum is mostly caused by respiratory tract infections, and corresponding therapeutic drugs can be selected according to different pathogens, and common pathogens include bacteria, viruses, tuberculosis, fungi, etc. The color of sputum may vary depending on the infecting bacteria. 1. Bacterial infections: according to the different bacteria, the color of sputum may vary, brownish yellow or rust-colored sputum is mostly caused by Streptococcus pneumoniae infections, golden-yellow sputum is mostly caused by Staphylococcus aureus infections, and yellow-green sputum is mostly caused by Pseudomonas aeruginosa infections. For Streptococcus pneumoniae infection, you can choose oral penicillin, amoxicillin and other antibiotics for treatment; for Staphylococcus aureus infection, you can choose oral cefadroxil, cefuroxime and other antibiotics for treatment; for Pseudomonas aeruginosa infection, you can choose piperacillin, amikacin, oxfloxacin, cefoperazone and other drugs for treatment. 2. Fungus: deep lung tissue infection caused by Candida albicans, Aspergillus and other fungal infections may lead to yellow sputum, which can be treated with fluconazole, itraconazole and other drugs. 3. Virus: Viral infections causing lung diseases usually do not need to be treated with antiviral drugs, and only need to symptomatically use aminoglutethimide and other drugs to reduce sputum; for people with clear immunodeficiency, they can choose to take ribavirin, oseltamivir and other antiviral drugs. 4. Tuberculosis: Tuberculosis infection should be treated with isoniazid, rifampicin and other medications under the guidance of a clinician at a specialized tuberculosis specialist or infectious diseases department. The above drugs should be used under the guidance of clinicians; the specific choice of drugs should be decided after bacterial culture and drug resistance test, do not use drugs without authorization.