Partial seizures are the local origin of abnormal discharges in the cerebral hemispheres, as opposed to generalized seizures, and are divided into three major categories: simple partial seizures, complex partial seizures, and partial secondary generalized seizures. The specific choice of medication is differentiated according to the age group of the patient: in the general adult, partial seizures are preferred to carbamazepine, but phenytoin sodium can also be used, but the latter is less used because of the current side effects. The second choice is sodium valproate, and gabapentin or lamotrigine, oxcarbazepine, and phenobarbital can also be used. In children with partial-onset seizures, oxcarbazepine is preferred, and only if oxcarbazepine is not available should carbamazepine and phenobarbital be considered. In partial-onset seizures in the elderly, gabapentin or lamotrigine are preferred, and carbamazepine is considered only if there is no condition for their use or if there is an allergy to these drugs.