Calf tenderness is generally associated with overwork, neurological lesions and soft tissue injuries, and can be relieved by medication, exercise therapy or surgery. 1. Overexertion: If you are often engaged in heavy physical labor or a lot of exercise, calf muscle fatigue will easily cause calf soreness and tenderness, which can be relieved by resting, stretching and massage. 2. Neurological lesions: when the lower extremity peripheral nerve injury or lumbar spine lesions such as lumbar disc herniation compression of the nerve root, it is easy to affect the motor and sensory function of the lower extremities, thus producing symptoms of calf tenderness, can be treated by taking nutritive nerve drugs, such as methylcobalamin or lumbar traction method of treatment. 3. Soft tissue injury: usually if the movement is not appropriate, the calf muscle soft tissue injury, easy to trigger the symptoms of calf tenderness, can be considered through the movement of stretching with the fascial knife and other methods of treatment. If the symptoms of calf tenderness persist for a long time, you need to consult a doctor for examination, you need to exclude varicose veins of the lower limbs, arterial embolism, heart failure and renal failure and other diseases, under the guidance of the doctor targeted treatment, to prevent the production of motor dysfunction in the later stage.