Gastric discomfort and foreign body sensation in the throat may be related to gastroesophageal reflux disease (GERD), you can take the following medications: 1, drugs to inhibit gastric acid secretion, such as omeprazole, etc., by inhibiting the secretion of gastric acid to reduce the reflux of gastric acid into the esophagus. 2, drugs to promote gastrointestinal motility, such as mosapride, etc., by promoting gastrointestinal motility to reduce the time of exposure of the food in the stomach to accelerate the peristaltic movement of the food to the intestinal lumen of the stomach. 3, mucous membrane protectants, such as aluminum sulfate oral solution. Such as aluminum sulfate oral solution, etc., after taking the formation of a protective film on the surface of the stomach, thereby reducing the possibility of reflux, the conditions of the best test there is no Helicobacter pylori infection. If the test result is negative, taking the above three types of drugs will be fine. If the test result is positive, it is necessary to use quadruple therapy to sterilize the bacteria, and after successful sterilization and improvement of symptoms, a small amount of acid-suppressing drugs can be used to maintain the treatment.