In today’s life, problems like cranial defects often occur because accidents are unpredictable and happen without notice, thus causing harm to oneself. It may be said that skull defect is not fatal, but it can greatly reduce the quality of life and quality of life, and long-term skull defect can cause more unexpected injuries. Moreover, the skull itself is a protective shield for the brain, when the skull is defective, then the brain will lose this layer of protection, and there is only a layer of scalp outside the intracranial tissues, which may be dangerous at any time. In addition, the integrity of the skull plays an important role in maintaining the stability of the intracranial pressure and intracranial environment, once the skull is defective the intracranial life activities may also be disturbed, so it is significant to go to the hospital for skull repair surgery in time. Because the skull plays a vital role for the whole body, it is like a defense wall for the brain, and when the skull defect occurs, the defense wall is destroyed, and the operation of various intracranial life activities can be implicated, which may damage the brain nerve function and induce a series of skull defect syndrome. Cranial defects deserve attention, and if they are left untreated for a long time, the consequences are even more unimaginable if secondary impacts occur accidentally. Therefore, patients should clearly realize that cranial defect is not an ordinary small problem, and timely treatment and repair in hospital is very crucial in order to reshape a stable cranial environment and avoid causing more damage to themselves. Of course, skull repair surgery is very strict, especially the choice of repair materials, which is related to the success or failure of the surgery, and cannot be sloppy at all. At present, titanium mesh is the most commonly used material in clinical practice, but it is not a suitable choice because it may cause infection and scalp abrasion after surgery, and interfere with the post-operative medical examination. Titanium mesh material has certain problems, a new type of polyether ether ketone peek material has appeared, it is a special polymer material with high stability, its various properties are close to the autologous skull, the postoperative effect is very good, and good protection, postoperative comfort is also very high, become the new trend of skull repair material.