You can take them together. In fact, they are both nutritional drugs. (Information) Methylcobalamin is an endogenous coenzyme B12, which is involved in the one-carbon unit cycle and plays an important role in the transmethylation reaction of methionine synthesis from homocysteine. Animal experiments have shown that it is easier to enter neuronal organelles than cyanocobalamin, participates in the synthesis of thymidine nucleoside in brain cells and spinal cord neurons, promotes the utilization of folic acid and nucleic acid metabolism, and has a stronger role in promoting nucleic acid and protein synthesis than cyanocobalamin; it can promote axonal transport function and axonal regeneration, and normalizes the transport of axonal skeletal protein in streptozotocin-induced diabetic rats’ sciatic nerve. It has an inhibitory effect on drug-induced neurodegeneration, such as axonal degeneration in mice induced by adriamycin, acrylamide and vincristine and neurological disease in spontaneously hypertensive rats. It has inhibitory effects; it can normalize delayed synaptic transmission and neurotransmitter reduction, and restore acetylcholine to normal levels in the brain of rats fed choline-deficient diets by increasing nerve fiber excitability and restoring ultimate plate potential induction. In vitro studies have shown that methylcobalamin promotes lecithin synthesis and neuronal myelin formation in cultured rat tissues. In addition to its use in the treatment of neuropathy, it is also used in the treatment of megaloblastic anemia due to vitamin B12 deficiency. It is not known whether this drug has teratogenic effects when taken during pregnancy. It is recommended to discontinue this drug after pregnancy, especially within the third month of pregnancy.