Uncontrollable blinking may be related to dry eye, conjunctivitis, Tourette’s syndrome, etc. Patients can be treated with medication and psychotherapy to improve the discomfort. 1. Dry eye: Uncontrollable frequent blinking of the patient may be caused by dry eye, the patient can follow the doctor’s instructions to use artificial tears such as sodium hyaluronate drops, etc., to lubricate the surface of the eye and relieve dry eye. 2. Conjunctivitis: Under the stimulation of inflammation, patients with conjunctivitis may experience foreign body sensation, photophobia, tearing and other discomforts, which may cause patients to blink continuously. Patients can follow the doctor’s instructions to use tobramycin eye drops, acyclovir eye drops, etc., to control inflammation and relieve eye discomfort. 3. Tourette’s syndrome: children with Tourette’s syndrome may have frequent blinking, accompanied by twitching of the corners of the mouth and other manifestations, children can follow the doctor’s instructions to ease the discomfort through psychotherapy, medication and so on, such as haloperidol, and so on. It is recommended that patients with Tourette’s syndrome should seek medical attention to assess their condition and treat them under the guidance of a doctor.