For patients with bone metastases from breast cancer, the five-year survival rate after treatment with chemotherapy and other methods is about 20%. Breast cancer is a common malignant tumor in women, and the disease can be caused by a variety of factors such as heredity and gene mutation. With the development of the disease, distant metastasis, such as bone metastasis, usually occurs in patients with advanced stages. Clinical manifestations such as bone pain and pathologic fracture can often occur in this period. As the condition of advanced breast cancer patients is more complicated and their physical condition is poorer, they are mostly treated by chemotherapy and other non-surgical therapies, and the commonly used chemotherapeutic drugs are cyclophosphamide, 5-fluorouracil, etc. The five-year survival rate of the patients after treatment is about 20%, and they are often combined with radiotherapy, targeted therapy and other methods of joint treatment.