It is possible for gallstones to become smaller, and some of them can be made smaller by dietary adjustments and medication. 1. Dietary adjustments: Gallstones are caused by increased cholesterol. If the patient eats low-fat, high-vitamin foods and drinks a lot of water, it can improve the composition of the bile, which may make the gallstones dissolve slowly and become smaller. 2. Medication: Some cholesterol stones can be dissolved slowly with the help of medication, commonly used medications include ursodeoxycholic acid, etc., which can make the gallstones smaller. Patients usually need to develop regular eating habits, not overeating, to avoid eating greasy food, can eat more high-fiber fruits and vegetables, eat less animal liver and other high cholesterol content of food. Normally, you can have appropriate physical exercise, which is conducive to weight control and physical fitness. Symptomatic cholelithiasis patients should undergo surgical treatment as early as possible, and the commonly used surgical methods are laparoscopic cholecystectomy, endoscopic retrograde pancreaticobiliary lithotripsy and so on.