Transverse colon with painful symptoms, the common causes are fecal stasis and tumor cell proliferation in the colon, as follows: 1. Fecal stasis in the colon: the colon with more fecal stasis will cause the intestinal tube of the colon to expand significantly, and the pressure in the intestine will increase, resulting in local painful symptoms. This is mostly seen in patients with chronic constipation and defecation difficulties, and can be done through appropriate enemas and oral laxative drugs to reduce intestinal pressure, promote intestinal contents excretion, and improve patients’ pain symptoms. 2. Tumor cell proliferation: If patients have tumor cell proliferation in the colon, it will cause intestinal lumen narrowing and incomplete obstruction. If the tumor invades the nerve, it will also cause intractable pain. Patients can clarify the specific location of transverse colon tumor through CT or colonoscopy, and perform surgical resection as early as possible. After surgery, chemotherapy and targeted therapy can be combined to improve the cure rate of surgery.