Chronic inflammation of the mucosa with mild intestinalization is a further development of chronic inflammation of the gastric mucosa with mild intestinal epithelial hyperplasia. Chronic inflammation of the mucosa usually refers to chronic inflammation of the gastric mucosa, that is, chronic gastritis. Intestinalization refers to intestinal epithelial hyperplasia, that is, the transformation of gastric mucosal cells into epithelial tissue of the small or large intestinal mucosa containing Paneth cells or cup cells. Intestinal hyperplasia is considered mild when it accounts for less than 1/3 of the glands and the epidermis, moderate when it accounts for a ratio of 1/3 to 2/3, and severe when it reaches more than 2/3. Chronic inflammation of the mucosa with mild intestinal chemosis is also known as mild intestinal epithelial hyperplasia of the gastric mucosa on the basis of chronic gastritis, which may be related to infections, alcoholism, high salt diet, smoking, etc. Helicobacter pylori infection is the most important cause of chronic gastritis and intestinal epithelial hyperplasia. When patients with chronic gastritis develop intestinal epithelialization, their risk of cancer increases. Therefore, if a patient develops chronic inflammation of mucosa with mild intestinal chemosis, it is recommended to consult a doctor in time and receive treatment actively to avoid delaying the condition.