The hazards of lung cancer interventional therapy are mainly some adverse reactions caused by drugs, such as skin damage, spinal cord injury and so on. Some patients can be complicated with pneumothorax and pleural effusion. Interventional therapy of lung cancer refers to a treatment method that guides drugs, radioactive substances or other physical therapeutic measures to tumor localization through certain auxiliary means. This method is easy to operate, with mild systemic adverse reaction and few complications, and is an effective palliative therapy. The hazards of lung cancer interventional surgery are mainly some adverse reactions caused by drugs, such as: 1. Skin damage: after bronchial artery infusion chemotherapy, erythema, rash and ulceration appear in the skin on the same side of lung cancer, which is caused by: ① high concentration of chemotherapeutic drugs causing arteritis of intercostal arterial branches, which leads to thrombosis, resulting in local ischemia and necrosis; ② chemotherapeutic drugs infiltrating into the local skin, which is damaging to the skin. 2. Spinal cord injury: it is the most serious complication of lung cancer interventional therapy. It often manifests as numbness and weakness of limbs, difficulty in urination, followed by paralysis of lower limbs and incontinence. (3) Esophageal-bronchial fistula: due to the high concentration of chemotherapeutic drugs given locally, so the chemotherapeutic drugs must be diluted and injected slowly. 4. Others: nausea and vomiting, impaired liver and kidney function, bone marrow suppression, etc. There are different degrees of fever and pain after lung cancer intervention, etc. Pneumothorax, pleural effusion, fever, pain, cough, hemoptysis, burns of skin at puncture site, etc. can also be complicated, the incidence rate is not high and the vast majority of them are mild. The same disease, the patient’s physical condition is different, different stages of the disease, the treatment method is different, should be standardized treatment under the guidance of the doctor.