Skin test-free tetanus shots are generally tetanus immunoglobulin, which is required for patients with a common tetanus antitoxin allergy. The price of tetanus immunoglobulin is between$200-$300, and patients do not need to have a skin test, or if they have a positive tetanus antitoxin skin test allergy, they can get a tetanus human immunoglobulin injection. For regular patients, if the tetanus antitoxin skin test is negative, the patient is first advised to get a tetanus antitoxin injection. Because for tetanus antitoxin, the treatment is also more effective and economical, patients are advised to have 1-2 injections of tetanus antitoxin. For patients who are allergic to the tetanus antitoxin skin test, tetanus human immunoglobulin injections are then considered. Injections are usually given as early as possible, within 24 hours of the injury, and the site of the injury requires local debridement and, if necessary, suturing.