Taking one capsule of Omeprazole per day may lead to adverse reactions such as decreased digestive function, atrophy of gastric mucosa, and decreased gastric secretion. Omeprazole belongs to proton pump inhibitors and is mainly used to treat gastritis, gastric ulcer, duodenal ulcer, stress ulcer, reflux esophagitis and other diseases. Prolonged use of omeprazole is likely to lead to decreased digestive function, gastric mucosal atrophy, gastric secretion function weakening and other lesions, and if taken for a longer period of time may also lead to more serious adverse reactions, including blurred vision, leukopenia, bone fracture, systemic lupus erythematosus and so on. It is contraindicated in people who are allergic to the product, infants and young children, people with severe hepatic or renal insufficiency, and patients using atazanavir. In addition, if patients have symptoms of dysphagia, black stools, blood in the stool or vomiting blood, they should consult their doctor whether they can use this drug. It is recommended to use the drug under the guidance of a doctor, not blindly self-medication to avoid adverse effects.