Symptoms of H. pylori infection vary depending on the degree of disease progression. Early stage may be asymptomatic; patients with gastritis and gastric ulcers may experience gastrointestinal symptoms such as abdominal pain, bloating and acid reflux. Most patients with H. pylori gastric disease do not have any symptoms in the early stage of infection, or only show mild digestive discomfort; long-term infected patients can induce epigastric pain, bloating, acid reflux, belching, nausea, vomiting, loss of appetite and other gastrointestinal symptoms; about 10% to 20% will progress to peptic ulcer, which manifests itself as a chronic, rhythmic epigastric pain in periodic episodes. A few develop into gastric cancer and gastric mucosal tissue-associated lymphoma, resulting in symptoms such as epigastric discomfort, fullness, pain or weight loss after eating. Infection with Helicobacter pylori should seek medical treatment as early as possible, improve the relevant digestive system examination and symptomatic treatment to avoid delaying the condition.