To discuss the effect of the sequence of pulmonary arteriovenous dissection during total thoracoscopic lobectomy on the outcome of stage I-II ttd,cell lung cancer. Methods We retrospectively analyzed the data of 277 patients who underwent direct total thoracoscopic lobectomy among I 134 patients who underwent lobectomy from September 2006 to December 2012 and had postoperative pathological confirmation of stage I-II tN,cell lung cancer. According to the order of vascular treatment, 152 patients were divided into the venous dissection group (Group V), 76 patients were divided into the arterial dissection group (Group A), and 49 patients were divided into the mixed arterial-venous-arterial dissection group (Group M). The preoperative and intraoperative conditions and postoperative survival and recurrence of the three groups were compared. The mean intraoperative bleeding in Group A was 109.9 m1, which was significantly less than that in Group V (157.5 ml), while that in Group M was 123.7 ml (P=0.027). The postoperative complication situation was similar in the operation time; the recurrence mode of he tumor was similar, and both were dominated by distant metastasis; the differences in tumor-free survival time and overall survival time were not statistically significant. Conclusion For the treatment of stage I-II non-small cell lung cancer under total thoracoscopy, treating and severing the artery first can reduce intraoperative bleeding and did not reduce surgical difficulty and postoperative complications; the order of vascular treatment did not affect tumor recurrence, metastasis and survival, and can be reasonably selected according to intraoperative needs.