There is a folk saying that if a wart grows on your body and several smaller ones grow next to it, the one that grows first is the mother wart and if you remove the mother wart, the other wart will fall off naturally. This statement is not scientific. A wart is a viral infection, and there is a sequence of onset, but there is no “male and female”. A wart is a superfluous epidermis caused by HPV (human papilloma virus) infection of the skin or mucous membrane. It can occur on any part of the body, but is mostly found on the back of the fingers, hands and feet. The virus is only found on the surface of the body. The virus is only in the epidermis and does not cause skin inflammation or enter the bloodstream, so the epidermis often coexists peacefully with the virus and the warts remain on the skin surface for a long time. Sometimes, after a wart is removed by microwave, laser, freezing or surgery, the other wart will automatically disappear. This is because when a wart is removed, the lesioned tissue causes the body’s immune system to respond by producing the appropriate immune substance, which causes the other wart to fall off, not because of the “mother wart”. A wart can be inoculated and spread by itself through a small break in the skin. In other words, the wart grows wherever the virus infects it. Because the first wart is long lasting and highly contagious, it appears to be the wart from which all other wart growths originate, so folk call it the “mother wart”. Avoiding trauma and skin breakdown is the main method of wart prevention. When wounds appear on the skin in general, do not scratch them with your hands and treat them promptly to prevent contamination of other skin with HPV exudate. Wart treatment is usually external and can be done with 5-fluorouracil ointment, 10% formalin, 20% glacial acetic acid or concentrated carbolic acid applied topically to the lesions twice daily. You can also choose 40% iodoside (herpes net), dimethyl sulfoxide solution and 20% to 40% iodoside cream topical application plus sealing package. Or herbal infusion can also be cleared. For patients with small numbers, physical therapy such as microwave, freezing and laser is the main treatment. Pay attention to avoid pressure and friction to prevent secondary purulent infection. It is recommended to go to a regular hospital dermatology department for treatment to avoid leaving scars.