Osteoarthritis of both knees refers to osteoarthritis of the knee joint, which requires medication, surgery and other treatments. 1. Drug treatment: patients need to apply non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen, celecoxib capsules, and flurbiprofen gel paste under the guidance of doctors. Some patients may need to inject glucocorticoids such as hydrocortisone and methylprednisolone into the joint cavity. 2. Surgery: For patients who have poor drug treatment and whose condition continues to deteriorate and has affected their daily work and life, they need to consider surgical treatment, and common surgical methods include arthroscopic cleaning, osteotomy, joint fusion, artificial joint replacement, and so on. 3. Other treatments: patients can also cooperate with doctors through hydrotherapy, heat therapy, massage, acupuncture, transcutaneous electrical nerve stimulation and other physical measures for treatment. Patients need to choose appropriate mobility aids, such as canes and crutches. Knee osteoarthritis is a progressive disease, patients should go to the hospital in time and strengthen the daily life management to avoid delay.