The same brain disease, a breakdown of the differences between Parkinson’s and Alzheimer’s disease in terms of etiology, pathogenesis, clinical manifestations, and treatment. The main cause of Parkinson’s is the degeneration of the substantia nigra in the brain. The substantia nigra secretes dopamine, and when the substantia nigra degenerates, the amount of dopamine secreted is not enough. If the amount of dopamine is less than 50% of the normal amount, the symptoms of Parkinson’s (tremor paralysis) begin to appear. Alzheimer’s disease (Alzheimer’s disease) is also located in the brain and is caused by a lesion in the hippocampus of the temporal lobe of the brain. If there is atrophy in the temporal lobe, the symptoms of Alzheimer’s disease (Alzheimer’s disease) will appear. Symptoms Differences Physical symptoms such as trembling, stiffness and slow movement are more obvious in Parkinson’s patients. Memory is generally not affected, but there are delays in thinking and acting, such as slower counting and slower response and coordination in getting up and opening doors. In addition, Parkinson’s patients may have psychological symptoms such as depression and anxiety. More than 60% of Parkinson’s (tremor palsy) patients have symptoms of depression and do not like to contact and interact with others. Patients with Alzheimer’s disease like to stay still most of the time and are reluctant to move; they always forget things, but they may remember things clearly when they were young; their personality suddenly changes, for example, they become calculating, get emotional easily and get sad easily; they do not want to stay in one place, but often do not remember the way and get lost easily. Treatment effects Parkinson’s (tremor palsy) disease is currently, can be treated with drugs and surgery. In terms of medication, levodopa preparation is the main treatment drug, which can effectively relieve the symptoms. In terms of surgery, brain pacemaker surgery can relieve Parkinson’s disease (tremor palsy, rigidity). Different Parkinson’s patients find the right treatment plan for their condition. Because the cause and pathogenesis of Alzheimer’s disease (Alzheimer’s disease) are not known, there is no specific therapy for treatment, and symptomatic treatment is the mainstay. This includes pharmacological treatment to improve cognitive function and memory impairment; symptomatic treatment to improve psychiatric symptoms; and good care to slow down the progression of the disease. Pharmacological and rehabilitation treatments are aimed at improving cognitive and memory functions, maintaining the patient’s independent living ability and improving the quality of survival.