The treatment of spinal demyelinating disease needs to first identify the cause so that it can be treated. There are three main categories of common causes: the first is secondary to other diseases, such as carbon monoxide poisoning, drug intoxication, vitamin B12 deficiency, or certain infections, and treatment in this area is directed at the primary disease, such as anti-infection and neurotrophic. The second group is related to immunity, the main drug application for the treatment of this kind of disease is hormone, often need to apply prednisone or methylprednisolone; immunosuppressant such as azathioprine, cyclophosphamide and so on. The third type of treatment is prophylactic immunoglobulins. There are also symptomatic treatments, such as fatigue or urinary and fecal disorders, painful spasms, etc., which are treated with appropriate drugs.