Bone metastasis is possible in advanced cancer, and patients with advanced cancer can develop metastasis in multiple parts of the body. Cancer cells are firstly confined to local organs, and as the tumor develops, metastasis to other organs may occur at a later stage. Bone metastasis means that the primary cancer is not located in the bone, but the cancer cells have metastasized to distant organs, which generally indicates that the primary cancer is in advanced stage. When bone metastasis occurs, patients may first experience localized pain or pressure pain, and bone metastasis usually causes swelling of surrounding soft tissues. With the progression of the disease, patients with multiple bone metastases are prone to pathological fracture in the middle and late stages. If spinal bone metastasis occurs in the advanced stage of the tumor, patients may also experience spinal cord or nerve root compression. After the occurrence of bone metastasis of advanced malignant tumors, patients still need to actively cooperate with specialists for treatment, through active and effective treatment can reduce the pain of patients and prolong the survival time of patients.