It is very common for patients to develop intractable erratic reflux in chemotherapy. Patients with persistent erratic reflux often choose acupuncture and oral Chinese medicine, acupuncture points, such as Tanzhong, Tiantou, Neiguan, Juqui, Diayu and other points to lower the reflux and stop erratic reflux, there is also a clinical method of blood cupping, acupuncture points are Liver Yu, Diayu, Spleen Yu, the effect is faster and relatively more obvious than the acupuncture. Chinese medicine is mostly used orally with the addition and subtraction of Xuanwei Dai Ochre Tang, with the addition of persimmon dipping to stop eruption, which is also very effective in clinical practice.