Multiple breast nodules refer to multiple breast nodules detected on imaging or clinical palpation, which are usually benign but may be malignant. Multiple breast nodules are a common breast disease in women, commonly found in proliferative lesions. Multiple nodules are benign in most cases, but further examination is needed to clarify the nature of the nodules, such as diagnosis by pathologic examination. Patients should follow up regularly to observe the changes of each nodule and rule out the possibility of any malignant nodule. It is recommended that patients should have a regular review in 3 to 6 months to ensure that each nodule has not grown or undergone malignant changes. Meanwhile, multiple nodules are related to the mood state, and it is recommended that patients should keep their moods happy.