Gallstones usually refers to gallbladder stones, most of the patients with gallbladder stones usually have no symptoms, a few patients will have abdominal pain, usually gallbladder stones combined with acute cholecystitis have obvious clinical symptoms, such as biliary colic, fever and nausea and vomiting. Most patients with gallbladder stones do not have clinical symptoms and are only found to have gallbladder stones during physical examination. A small number of patients with severe conditions may show signs of abdominal pain, such as distension and discomfort in the right upper abdomen on weekdays, episodes of abdominal pain at night, and episodes of abdominal pain after a full meal and eating fatty foods. When gallbladder stones are combined with acute cholecystitis, there are obvious clinical symptoms, such as biliary colic, fever and nausea and vomiting, etc. The biliary colic is located in the right upper abdomen, and it can also radiate to the right shoulder, scapula and back, and it can be accompanied by gastrointestinal symptoms such as loss of appetite, anorexia, constipation, etc. The patient is recommended to have a thorough examination of the patient’s condition, and to have a good understanding of the symptoms. It is recommended that the patient go to the hospital to improve the examination and treatment under the guidance of the doctor.