Chai Hu plus Huang Lian is effective in relieving bitter mouth when waking up in the middle of the night caused by stomach fire and damp-heat in the liver and gallbladder (damp-heat evils accumulated in the liver and gallbladder). However, it is not effective for other causes of waking up in the middle of the night with bitter mouth. If you need treatment, you need to follow the doctor’s instructions to standardize the use of drugs. 1. Chai Hu has the effects of relieving fever and fever, relieving the liver of depression (treating depression by unblocking the liver’s qi), and elevating yang qi. It is indicated for treating superficial fever, Shaoyang syndrome, liver depression and stagnation of qi (poor qi and blood transportation of the liver, emotional and emotional depression), qi deficiency and subsidence, and prolapse of organs. Chai Hu is contraindicated or used with caution in cases of yin deficiency and hyperactivity of yang (deficiency of yin fluid and hyperactivity of yang), internal movement of liver wind, yin deficiency and hyperactivity of fire (deficiency of yin essence in the body and hyperactivity of deficiency fire), and qi upward reversal. 2. Huang Lian has the effect of clearing heat and drying dampness (removing heat and drying dampness), diarrhea and detoxification (removing fire and toxicity in the body). It is used for treating damp-heat plumpness (stomach distension and discomfort), vomiting and acid swallowing (swallowing the acid in the stomach that rushes upward to the mouth and throat), damp-heat diarrhea (diarrhea caused by feeling damp-heat evils), high fever and dizziness, and disturbed sleeplessness (disturbed heat in the heart and the symptom of insomnia). Yellow dock is contraindicated for those who are weak and cold in the spleen and stomach. Bitterness and dryness easily injure yin and fluids, so be cautious of using Huanglian for those with yin deficiency and fluids injury. If the symptoms of waking up in the middle of the night with bitter mouth are not relieved for a long time or accompanied by other discomforts, consult a doctor in time to find out the cause and carry out targeted treatment.