The reasons for getting up in the morning with white mucous membrane in the mouth may be physiological factors such as body metabolism as well as pathological factors such as gastrointestinal dysfunction, lip inflammation and so on. 1. Physiological factors: after falling asleep at night, due to the body’s metabolism will cause loss of moisture in the oral cavity, lips and respiratory tract, dry lips will lead to the shedding of lip cells, the symptoms of white mucous membrane. Patients should drink more water, eat more fresh vegetables and fruits, and apply lipstick before going to bed to reduce the symptoms. 2. Pathologic factors: (1) gastrointestinal dysfunction: due to improper diet caused by indigestion, loss of appetite and increased mucosal secretions, resulting in the appearance of white mucous membrane in the mouth, the patient can follow the doctor’s instructions to take omeprazole, bifidobacteria triple live bacterial capsules to alleviate the symptoms. (2) Lipitis: due to bad dietary stimulation, contact with cosmetic allergies, etc. can cause lipitis, manifested as dry lips, skin and white mucous membrane, etc., patients can follow the doctor’s advice to use tacrolimus ointment, pimecrolimus cream, etc. for treatment. If you wake up in the morning with white mucous membrane in the mouth symptoms continue to be unrelieved in time to clarify the cause of the disease, diagnosis and treatment, so as not to delay the condition.