Since uric acid is influenced by diet and metabolism (liver and kidney), it is necessary to analyze and manage the decrease in blood uric acid in combination with other clinical manifestations. Uric acid is a metabolite of purines in nucleoproteins and nucleic acids, which can come from the body or from food, and the liver is the main site of uric acid production; very little of it is broken down in the liver and eliminated from the body with bile excretion and feces, and most (more than 90%) of blood uric acid needs to be excreted by the kidneys. Possible reasons for lower blood uric acid concentrations include reduced food intake due to various reasons, reduced renal tubular reabsorption of uric acid, and reduced uric acid production due to liver damage. Therefore, there is no need to be nervous about low blood uric acid. If you observe a persistent decrease you can go to the appropriate department for examination and treatment.”