Bilirubin is high more than 200umol/L, need to be combined with other tests to determine the cause of the disease, such as hepatitis, cirrhosis, cholecystitis, etc., need to be prescribed to protect the liver, anti-inflammatory and other treatments. 1. Hepatitis: it can be seen in acute jaundice hepatitis, chronic active hepatitis, etc. It can be treated with hepatoprotective and enzyme-lowering treatments according to doctor’s prescription, and commonly used medicines include glutathione and dicyclomine. 2. Cirrhosis: except for liver protection and enzyme-lowering treatment, anti-fibrosis treatment is also needed, such as oral prednisone and so on. 3. Cholecystitis: bile acid drugs, such as ursodeoxycholic acid capsule, and anti-infection treatment can be applied. High bilirubin of more than 200 umol/L should be combined with indirect bilirubin and direct bilirubin to determine the type of obstruction, combined with blood routine, liver function, abdominal ultrasound and other related examinations to clarify the cause of the disease. If the bilirubin is high 200umol/L, you need to keep a light diet in daily life, eat less animal offal and fried food, quit smoking and drinking, and according to the cause of the disease, follow the doctor’s instructions to give the cause and symptomatic treatment, such as hepatoprotection and anti-inflammatory treatment.