Long-term use of Omeprazole carries the risk of carcinogenesis, but Omeprazole may have other side effects such as dry mouth, nausea, vomiting and insomnia. Omeprazole is a proton pump inhibitor, the main effect is to inhibit the secretion of gastric acid in the gastric mucosa, which is mainly used in the treatment of reflux esophagitis, peptic ulcer, acute and chronic gastritis. Currently, some studies show that long-term administration of omeprazole in patients with Zuoai syndrome has a carcinogenic effect. There may be some side effects of taking omeprazole, such as gastrointestinal discomforts such as nausea, vomiting, dry mouth, and bloating; neuropsychiatric symptoms such as dizziness, headache, insomnia, and sensory abnormalities; and hematologic risks such as anemia and hypomagnesemia. It is also contraindicated for those who are allergic to the drug and those with severe renal insufficiency. For digestive and other discomforts, it is recommended to go to a regular hospital and take the medicine under the guidance of a professional doctor.