The different shapes of temperature curves formed when the body temperature of a febrile patient is measured routinely and labeled on a temperature sheet are known as thermotypes. Heat pattern is one of the manifestations of the interaction between pathogenic factors and the organism, and many febrile illnesses have a relatively specific heat pattern, so the typical heat pattern is very valuable for the diagnosis of the disease. The pre-morbid health condition is poor, most of them are accompanied by primary diseases that affect the body’s defense function, and more of them are hospital-acquired infections. Chills, high fever, profuse sweating, and bimodal fever is more common, and there are occasional cases of trimodal fever, which is rare in sepsis caused by other pathogens and deserves attention. How to differential diagnosis of three-peak fever? 1, respiratory viral infections This group of diseases accounts for 70%-80% of acute respiratory diseases. Caused by rhinovirus, influenza virus post-influenza virus adenovirus, respiratory syncytial virus. echovirus coxsackievirus, etc., and its clinical characteristics of a variety of manifestations. Most of the symptoms of upper respiratory tract infections are mild while symptoms of fine bronchitis and pneumonia are more severe. Diagnosis is mainly based on clinical manifestations, white blood cell count and X-ray examination and response to antibiotic treatment, etc. In recent years, due to the progress of diagnostic technology, immunofluorescence and enzyme-linked immunosorbent assay (ELISA) rapid diagnostic methods can be used to determine the pathogen. Commonly, there are influenza, common cold, glandular pharyngeal conjunctival fever, herpes pharyngitis, bronchiolitis, pneumonia and so on. Must be differentiated from respiratory bacterial infections. 2, Severe Acute Respiratory Syndrome (severeacuterespire-atory, syndrome, SARS) The disease was first introduced in November 2002 in China’s Guangdong Province, is a coronavirus-induced fever respiratory symptoms as the main manifestation of a clearly contagious pneumonia, severe patients are prone to rapid progression of acute respiratory distress syndrome (ARDS) and death. Patients with severe disease are prone to rapidly progress to acute respiratory distress syndrome (ARDS) and die. For SARS epidemiological basis of fever, respiratory symptoms and pulmonary signs, and lung X-ray CT and other abnormal imaging changes, can exclude other diseases diagnosis, can make SARS clinical diagnosis in the clinical diagnosis of the basis, if the secretion of the SARS coronavirus RNA (SARSCOVRNA) test positive, or serum SARSCOV antibody positive or antibody titer four times and above increase, then the diagnosis can be confirmed. 3, sepsis In suffering from primary infection foci, the emergence of generalized sepsis symptoms, and multiple migratory abscesses to help diagnosis should be vigilant that the primary infection foci can be very mild or have healed. Therefore, when encountering acute high fever of unknown cause, accompanied by chills or chills and sweating, heavy systemic symptoms of toxicity, leukocytosis and nuclear left shift in the blood without parasitic findings, no special signs and symptoms, should be considered as this disease timely blood culture, to find the foci of infection and migratory foci (lungs, skin, etc.) The causative organisms to the Staphylococcus aureus is common, the second for the Escherichia coli and other intestinal Gram-negative bacilli.