The best drugs to use to lower uric acid are: 1) sodium bicarbonate to alkalize urine; 2) drugs to promote uric acid excretion, such as the commonly used benzbromarone tablets, 50mg, once a day; 3) drugs to inhibit uric acid secretion, commonly used are allopurinol tablets, which can be taken 1-2 times a day, twice a day orally; febuxostat is also a drug to inhibit uric acid secretion. If you have high uric acid and no gout attack, you don’t need to use colchicine or pain relieving drugs. It is recommended to drink more water during the period of taking uric acid lowering drugs, drink 2000ml of water daily and have a low purine diet.