What do you know about egg freezing?

Egg freezing is actually the removal of mature eggs from a woman’s body and preserving them in liquid nitrogen using cryoprotectants. What are the requirements for egg freezing? Currently, “egg freezing” falls under the category of assisted reproductive technology. This is clearly defined by law in China. You must have “two certificates” (marriage certificate and ID card). Only couples who are suffering from infertility can be treated with assisted reproductive technology. There are strict rules for egg freezing in assisted reproductive technology, and the country has not yet approved the freezing and preservation of gametes or embryos for unmarried women or couples with normal fertility. In view of the safety of egg freezing, the regulations issued by the Health and Welfare Commission in 2013 stipulate that egg freezing can only be considered in the following two cases: first, couples with a history of infertility and evidence of assisted conception, in special cases where the husband fails to retrieve sperm on the day of egg collection and does not accept donor sperm; second, cancer patients who wish to preserve their fertility can have their eggs frozen prior to surgery and chemotherapy. What are the main steps of egg freezing? In order to freeze the eggs, the first step is to retrieve them; in order to retrieve them, the first step is to promote ovulation. In clinical practice, women are usually given gonadotropin injections for 9-12 days, while follicle monitoring and blood hormone level monitoring under ultrasound are performed. When the follicles are mature, egg retrieval is performed by puncture needle under ultrasound guidance. The oocyte mass is picked up from the follicular fluid, degranulated and mature eggs are selected for freezing. When the time is right and the patient requests fertility treatment again, the frozen eggs are resuscitated, fertilized in vitro with the male partner’s sperm, grown into embryos, and selected for transfer with good quality embryos, while the remaining embryos are frozen for conservation. Since the birth of the world’s first slow-frozen egg in 1986, more than a hundred IVF babies have been successfully conceived using the “frozen egg” recovery technique worldwide. There is no data yet on the future health of these children and whether they will be potentially affected by “egg freezing”. Nowadays, more and more young women, from celebrities to people, are thinking of freezing their eggs to buy a good “regret pill” for their infertility. In fact, the recovery rate of frozen eggs is not as high as the recovery rate of embryos, and the fertilization and eugenics rates of recovered eggs are not as high as those of fresh eggs. At the same time, older mothers face more obstetric complications and perinatal risks as they age. Egg freezing is not a conservation magic bullet and our advice is to have children at an appropriate age.