The causes of gastrointestinal spasms are acute gastroenteritis, overeating, spicy and cold stimuli, etc. The medications that can be taken are antispasmodics, antiemetics, pain relievers and so on. 1. Antispasmodic drugs: atropine, scopolamine, etc. are more commonly used to inhibit smooth muscle spasm of the gastrointestinal tract. 2. Antiemetic drugs: vomiting severe cases can use antiemetic drugs, metoclopramide, chlorpromazine, etc. are more commonly used. 3. Painkillers: Gastrointestinal spasms often lead to pain, and unauthorized use may mask the condition. After the cause of the disease is clear, can be appropriate to use aspirin and other anti-inflammatory analgesics. The above drugs need to be used under the guidance of a doctor, the specific treatment program, need to be guided by a doctor in order to better treat the disease.