Shi Huida generic drug name is levamlodipine benzenesulfonate, long-term oral amlodipine benzenesulfonate replacement for which antihypertensive drug is good to be formulated according to the condition. Levamlodipine benzenesulfonate is a calcium antagonist, has a dilating effect on coronary arteries and peripheral blood vessels, the main indications are hypertension and coronary heart disease. Oral levamlodipine benzenesulfonate patients with poor results, or patients who can not tolerate the adverse effects, can be replaced with other antihypertensive drugs, there is no one drug is better, it depends on which drug is more suitable for the patient. Patients with high blood pressure who have a fast heart rate can be replaced with metoprolol, which can slow down the heart rate while lowering blood pressure. Patients with hypertension with cardiac insufficiency can be replaced with hydrochlorothiazide, which lowers blood pressure and has a diuretic effect at the same time. It can also be replaced with valsartan, which inhibits cardiac remodeling while lowering blood pressure. Adverse reactions to levamlodipine benzenesulfonate include flushing, tachycardia, edema of the ankles, dry stools, etc. It is contraindicated in patients who are allergic to the components of the drug, and those who have low blood pressure. Replacement of levamlodipine benzenesulfonate with other antihypertensive drugs should be done under the supervision of a physician, avoiding self-medication.