Severe folliculitis can be treated by strengthening skin care, regulating diet and using drugs. 1. Strengthen skin care: severe folliculitis has a certain relationship with infectious factors, mainly due to Staphylococcus aureus and Staphylococcus epidermidis, usually to strengthen skin care, keep the skin clean and prevent infection. 2. Regulate diet: severe folliculitis will lead to local pain, may also be accompanied by itching and pus infection, the patient can not eat chili, ginger, garlic and mustard and other stimulating food, so as not to produce local irritation, resulting in aggravation. 3. Use of drugs: patients with severe folliculitis need to be coated with isotretinoin combined with antibiotic drugs under the guidance of a doctor for treatment, common anti-external antibiotics generally have levofloxacin hydrochloride ointment, erythromycin ointment and so on. For patients with severe infections, oral antibiotic drugs are also needed, such as cefixime capsules, azithromycin capsules and so on. Patients with severe folliculitis need timely medical treatment to prevent further aggravation of the disease, and the above medications need to be used under medical supervision.