Sodium tripolyphosphate is a common food additive that is harmless to humans when ingested in safe doses; excessive intake or large exposure may cause digestive discomfort, mucous membrane damage and other hazards. Sodium tripolyphosphate is a food additive, which is allowed to be added into food or drugs as water retention substance. Normal intake of safe doses of this substance through food or drugs is harmless. However, if excessive intake of the substance exceeds the safe dose, it will be hazardous to health. On the one hand, phosphate can cause water loss in the epithelium of the digestive tract and irritate the mucous membrane of the digestive tract, resulting in abdominal pain, vomiting and diarrhea, and on the other hand, the substance can cause damage to liver and kidney functions. In vitro, if the substance comes into contact with exposed mucous membrane tissues such as the cornea, it may cause localized redness, swelling, pain and other allergic manifestations. It is recommended to go to the hospital promptly if the above symptoms occur or if you have been exposed to the substance in excess.