Prolonged vomiting in patients with pyloric obstruction will cause a large amount of gastric acid loss, due to the loss of gastric acid patients will have alkalosis, manifested in patients with low potassium, low chlorine and alkalosis, at this time the patient will have confusion, impaired consciousness, and even weight loss, emaciation, dehydration and other related symptoms. Therefore, patients with pyloric obstruction must pay enough attention to the need for timely improvement of gastroscopy to clarify the specific causes of pyloric obstruction. If the pyloric obstruction is caused by local scar tissue hyperplasia, it is a common benign lesion, and the prognosis of the patient is often better after surgical resection of the local benign lesion. However, if the patient is obstructed by the pyloric tumor hyperplasia, the patient needs to undergo a radical tumor surgery, which needs to be performed to remove regional lymph nodes, and after the surgery, the patient needs to be treated with chemotherapy, radiation therapy, targeted therapy, and so on.