Estradiol is not normal at 5000 pmol/L. Estradiol is one of the most active hormones in the body. The concentration of estradiol varies somewhat with the menstrual cycle, but as long as it is within the normal range, treatment is not necessary. The concentration of estradiol during puberty is about 0-121pmol/L, during follicular phase is about 37-330pmol/L, during ovulation is about 367-1835pmol/L, and during luteal phase is about 184-881pmol/L. The concentration of 12 inches is different at each stage, so be sure to go to the hospital regularly for relevant examinations. Estradiol concentration of 5000 pmol/L refers to the appearance of ovarian over-excitation problems, and it is recommended to go to the hospital for timely conditioning treatment to avoid harm to the body.