Bone tuberculosis belongs to the lesions caused by tubercle bacillus infection of bone, advanced bone tuberculosis generally speaking, the lesion is relatively late, there will be obvious local bone destruction, sometimes accompanied by obvious cold abscess. For the advanced stage of bone tuberculosis, it is necessary to improve the local CT, if necessary, magnetic resonance examination to accurately determine the degree of local lesions and the scope of involvement. Regular anti-tuberculosis treatment, such as isoniazid, rifampicin, and in most cases surgery should be considered. In the case of spinal tuberculosis, internal fixation with bone grafting is an option. In the case of joints, fusion of the joints may be an option. In addition to surgery and anti-tuberculosis treatment, active nutritional support is also needed, and eating more high-protein foods, such as lean meat, fish soup and eggs, will help recovery.