Gray nail is caused by fungal infection, because the drug is not easy to enter the deck and the nail growth is slow, so the nail fungus with ointment or internal drug treatment is more difficult, the key is to adhere to the medication. Gray nails are called onychomycosis, a deformation of the nails caused by fungal infection of the nail roots. Commonly used fungicidal creams are ketoconazole cream, bifonazole cream, etc., which are mainly used to treat fungal skin diseases, such as lichen planus and ringworm. Because the drug is not easy to enter the nail plate and the nail growth is slow, so the treatment of tinea pedis is more difficult, and the key lies in the persistence of medication. 1. external drug treatment: first use knife or nail file to remove as much as possible the sick nail, then use 30% glacial acetic acid solution or 3%~5% iodine tincture, 2 times a day, until the new nail grows out; can also use 40% urea ointment sealing package to make the sick nail soften peeling off, then use antifungal preparation such as 8% cyclopiazepine, 5% amorphophallus nail applicator. 2. Systemic drug therapy: Itraconazole dispersible tablets intermittent shock therapy, nails need 2~3 courses, toenails need 3~4 courses; terbinafine tablets continuous consumption, nail course 6~8 weeks, toenail course 12~16 weeks. Combined treatment with topical drugs can improve the efficacy. Gray nail treatment needs to be under the guidance of a professional doctor to use medication, during the treatment is not recommended to drink alcohol, avoid using other people’s nail clippers or shoes and socks.