What is the cause of persistently high white blood cells but no fever?

Persistently high white blood cells without fever have physiologic and pathologic causes, and common causes such as exertion, strenuous exercise, urinary tract infection, upper respiratory tract infection, blood system diseases, etc.
1. Mildly elevated white blood cells are mostly caused by physiologic factors or some mild infections. Physiological factors include strenuous exercise, overwork, heat or cold stimulation, women’s menstrual period or pregnancy, etc. Generally, no special treatment is needed.
2. Infections caused by high white blood cells but not fever are mainly: urinary tract infections, upper respiratory tract infections, etc., which can be accompanied by urinary urgency and frequency, cough and runny nose and other discomforts, blood tests can be found to be high in white blood cells, but they do not always have fever, and can be improved by anti-infective treatment (levofloxacin).
3. If the white blood cells are obviously elevated, excluding infection and other factors, we need to be alert to chronic lymphoproliferative diseases or myeloproliferative diseases, such as chronic lymphocytic leukemia, chronic granulocytic leukemia, myelofibrosis, etc. There are some patients with the above mentioned diseases who really do not have any uncomfortable symptoms, but diagnosed because of the obvious elevation of the white blood cells found during the physical examination.
Therefore, if the white blood cells are persistently high without fever, it is recommended to consult a doctor in time, complete the relevant examinations, and clarify the specific causes under the guidance of a physician.