Nasopharyngeal cancer may cause pain in the back of the neck. Nasopharyngeal cancer is a relatively common malignant tumor of the head and neck. There are many clinical symptoms, the more common ones are nasal congestion, runny nose, and possibly nasal discharge with blood. Some patients may have enlarged lymph nodes in the neck, which may cause pain in the back of the neck. There are many causes of pain in the back of the neck, including pain caused by local lymph node metastasis, pain caused by cervical metastasis of nasopharyngeal cancer, and involved pain caused by the primary lesion of nasopharyngeal cancer. It is recommended to go to ENT or oncology department after such symptoms appear, and CT or MRI of the neck should be done to clarify the specific lesion. In terms of treatment, nasopharyngeal cancer is mainly treated with a comprehensive treatment plan of radiotherapy and chemotherapy, and regular follow-ups are needed after treatment to observe the treatment effect.