Patients with lymph node hyperplasia at the base of the tongue, generally speaking, depending on the nature of the lymph node hyperplasia, different clinical treatment methods can be adopted. First, if the patient with ulcers and chronic inflammatory blisters at the base of the tongue, resulting in localized infection, caused by the lymph node hyperplasia at the base of the tongue. At this time, you can take amoxicillin and watermelon cream tablets to promote the healing of the ulcers at the base of the tongue and the inflammatory blisters slowly subside. After controlling the local infection, the hyperplasia of lymph nodes can be absorbed by itself and will not cause serious complications. If the root of the tongue is invaded by malignant tumors, resulting in cancerous hyperplasia of lymph nodes. In this case, patients need to complete CT examination as soon as possible to clarify the location of the primary tumor, and then perform tumor resection combined with local chemotherapy and radiotherapy to kill the cancer cells in the body, which can achieve a better therapeutic effect.