Trimethoprim maleate tablets can cause gastrointestinal adverse reactions if taken too much, and serious adverse reactions such as toxic effects on human liver and kidney function. 1. Gastrointestinal adverse reactions: Trimethoprim maleate tablets is a calcium antagonist gastrointestinal antispasmodic drugs, gastrointestinal smooth muscle has a two-way regulatory effect, eaten more than the inhibition of gastrointestinal function, resulting in gastrointestinal discomfort, dry mouth, diarrhea and other symptoms. 2. Liver and kidney function toxic effects: the main metabolism of the drug excretory organs are the liver and kidneys, when the dose of drugs taken in excess of the seriousness of the liver and kidneys can not be metabolized, but also on the liver and kidney function, resulting in serious damage, functional abnormalities. Taking too much of any drug will produce certain side effects that are not favorable to one’s health. In the case of overdose, you should stop taking the drug immediately, and if you have serious adverse reactions, you should go to the hospital immediately, so as not to delay your condition.