Patient Question: Disease:Alzheimer’s Disease Description:My mother is 66 years old and has been ill for about three or four years. Initially, she was forgetful and the family did not realize that she was ill, but only in the last two years did she realize that she had Alzheimer’s disease. The current symptoms are: memory loss, former colleagues and friends are not recognized. I only know a few people around me. I don’t know the names of common household items, and I don’t know how to use them. Calculation ability is very good. He is able to take care of himself, can cook, mop the floor, wash clothes, needs company when he goes out, and can walk around his home by himself. Poor reaction and comprehension, can’t understand episodes of TV dramas etc., can’t understand. I had a brain CT, and it was said that there was atrophy of the E pagina. I would like to know if my mother’s condition is moderate or severe dementia. 2. What kind of medicine should I take? How to take it? Reply from Lulu Zhang, Department of Psychiatry, Guangzhou First People’s Hospital: In your case, your mother may have moderate dementia (a psychiatric examination and assessment of the relevant scales are required to accurately determine her current level of dementia). If the dementia is Alzheimer’s disease, it is a group of primary degenerative brain degenerative diseases that progress slowly and irreversibly, with a predominance of intellectual impairment. At present, there are no specific medications available, but the main treatment is medication to improve cognitive function (e.g., meperidine, Amlixan, etc.), and at the same time, attention should be paid to the care and maintenance of this type of elderly people, often giving relief and auditory and visual stimulation, and allowing them to play simple educational games. If your mother has a history of hypertension or cardiovascular disease, it is best to have a cranial MRI to rule out vascular dementia. Vascular dementia generally progresses slowly and has a fluctuating course, often with acute exacerbation caused by stroke. The treatment should focus on blood pressure control and treatment of the primary cerebrovascular disease, together with medication to improve cognitive function.