Dry cough without sputum shortness of breath may be caused by acute respiratory infections such as bronchitis, pneumonia; chronic airway diseases such as asthma, pulmonary fibrosis, etc. Cough suppressants, bronchodilators, glucocorticostimulants, and anti-infective drugs need to be used according to the cause. 1. Bronchitis: If the dry cough without sputum and shortness of breath is caused by bronchitis, dextromethorphan and pentoxyverine can be given to relieve the cough. Give albuterol, terbutaline and other bronchodilators to relieve shortness of breath. Combined bacterial infection can be combined with antibiotics such as cefuroxime, levofloxacin and so on. 2. Pneumonia: Dry cough without sputum and shortness of breath may also be caused by pneumonia, which can be treated with anti-infective drugs such as amoxicillin and cefaclor under the guidance of a doctor. Licorice tablets can also be given to relieve cough. 3. Asthma: patients often have symptoms such as wheezing, shortness of breath, cough, chest tightness, etc. Inhaled glucocorticosteroids combined with long-acting β2 agonists such as budesonide formoterol for inhalation can be used to control symptoms. 4. Pulmonary fibrosis: patients may have progressive dyspnea, dry cough and other symptoms, can be given symptomatic antifibrotic drugs such as nidazanib, pirfenidone, if the combination of primary diseases such as rheumatic immune disease, can be added oral glucocorticosteroids and immunosuppressants such as methotrexate. The causes of dry cough are complex and varied, it is recommended to actively seek medical attention to clarify the cause of the disease and standardize the treatment, avoid self-medication.