Diabetes Series Knowledge

  As more and more attention is paid to diabetes, many diabetic patients have more knowledge about blood glucose management, especially the increasing concern about glycated hemoglobin, many patients may still have questions, what can glycated hemoglobin reflect? The product of the combination of hemoglobin and blood sugar in the red blood cells of human blood is glycated hemoglobin, so it is proportional to the blood sugar concentration and can be maintained for about 120 days, and the blood sugar concentration before 120 days can be observed. Therefore, we would recommend diabetic patients to have glycosylated hemoglobin measurement every 3 months to know the recent blood glucose control.  But for some special diabetic patients, such as type 1 diabetes, type 2 diabetes with high fragility, does the glycosylated hemoglobin control mean perfect glycemic control?  Here I will tell you a real story: Xiao Liu is a 30-year-old type 1 diabetic, she has been suffering from the disease for 10 years, she has learned a lot about diabetes, she is at the right age for pregnancy, in order to be able to carry a healthy baby, she wanted to be hospitalized for a comprehensive examination to prepare for pregnancy according to the doctor’s previous instructions. After admission, the result of glycated hemoglobin was 6%, she felt very happy, but her own blood glucose monitored before was sometimes over 20 after meals, and sometimes as low as 2 points before meals, was her blood glucose good or bad? The 24-hour ambulatory glucose monitoring told her the answer: This picture tells us that although the glycated hemoglobin is good, her blood glucose is not perfect, and there are hypoglycemia as well as hyperglycemia that are not felt beyond the point blood glucose that is not monitored, so for such type 1 diabetes patients, glycated hemoglobin cannot reflect the actual blood glucose control of the patient, and after the ambulatory glucose monitoring with insulin pump precision After the adjustment, the blood sugar fluctuation is reduced and the hypoglycemia and hyperglycemia are basically lifted.  Therefore, regular (3 months) glycated hemoglobin test must be combined with usual blood glucose monitoring to judge the good or bad blood glucose control, and dynamic blood glucose monitoring is needed if the blood glucose fluctuation is large or frequent hypoglycemia, and the cause of early morning hyperglycemia is unclear. Dynamic blood glucose detection system is the latest high-tech product, which automatically records blood glucose every 5 minutes, detects dynamic blood glucose changes within 72 hours, draws a precise daily blood glucose change curve, and marks events such as diet and exercise on the curve. Through this comprehensive, detailed and complete blood glucose map, it provides important clues for timely clinical diagnosis and reasonable treatment.  Our department has three American Medtronic dynamic blood glucose monitors, which have played a great role in analyzing the causes of high and low blood glucose in diabetic patients and guiding clinical medication over the years, and the islet pump combined with dynamic blood glucose monitoring (double “C” therapy) in the treatment of diabetes is in the leading treatment position in northeastern provinces. The all-day blood glucose stabilization allows more diabetic patients to achieve perfect blood glucose control and greatly reduces the risk of occurrence and development of various acute and chronic complications.