Treatment of bone tuberculosis is comprehensive, with the following specific treatments: 1. supportive treatment: pay attention to rest and nutrition; 2. anti-tuberculosis drug therapy, which determines the use of drugs and duration of drug administration according to the patient’s age, lesion dissemination and concomitant symptoms, and can be combined with a variety of drugs, including isoniazid, rifampin, ethambutol and pyrazinamide. If drug resistance occurs, treatment with fluoroquinolone drugs and amikacin, kanamycin or capreomycin injection is required for 12-18 months, treatment is not only limited to the patient himself, but also the patient’s family and his close contacts should be well protected, once the tuberculin test is positive drug treatment should be considered, treatment time is longer, liver function needs to be reviewed regularly to avoid liver damage; 3. In anti-tuberculosis timely surgical treatment under the control of anti-tuberculosis drugs, including arthrotomy, bone scraping and implantation of extra-articular bone lesions, arthrodesis, osteotomy, soft tissue abscess incision and drainage or incision, joint fusion, and amputation.