There are not only 4 reasons for postmenopausal breast swelling and pain, the common ones are perimenopausal syndrome, mastitis, breast hyperplasia or breast cancer, etc. The most common ones are perimenopausal syndrome, mastitis, breast hyperplasia and breast cancer. 1. Perimenopausal syndrome: When ovarian function decreases before and after menopause, sex hormone levels drop significantly, which can easily lead to perimenopausal syndrome, which may cause postmenopausal breast swelling and pain after being affected by endocrine and neurological factors. 2. Mastitis: Mastitis can be induced by bacterial infection in the breast area, and after being stimulated by inflammation, it can also affect the breast area and cause postmenopausal breast swelling and pain. 3. Mammal hyperplasia: stress or prolonged smoking and alcohol abuse may lead to endocrine hormone metabolism imbalance, which can cause continuous stimulation of the mammary glands and lead to mammary gland hyperplasia. This disease can also lead to abnormal enlargement of the mammary glands causing the above symptoms. 4. Breast cancer: patients affected by heredity and radiation and other factors may cause breast cancer, and as the tumor continues to grow, it may cause pressure on the breast area and the above symptoms may also appear. Postmenopausal breast swelling and pain may also be caused by benign breast tumors or paratesticular breasts, etc. Patients should go to the hospital in time to choose the appropriate method of treatment.