Red bumps on the thighs with itchy symptoms may be caused by eczema or urticaria, which should be avoided by contact with allergens, as well as allergic and spicy foods such as seafood, chili, fennel, onion, raw garlic, etc. Excessive scratching and friction should be avoided to avoid infection and breakage. In this case, you can first take oral antihistamines, such as loratadine, or alternatively, you can choose to take similar drugs orally. If the red bumps on the thighs are painful, infectious lesions, such as sebaceous cyst infection and folliculitis, should be treated with sensitive antibacterial drugs, mainly cephalosporins and penicillins and macrolides, and in severe cases, intravenous drip treatment. If the activity is obvious, local wet compresses with magnesium sulfate can be considered. If abscesses are formed, timely incision and drainage are needed to remove necrotic material, and repeated flushing with hydrogen peroxide, iodophor and saline is applied to promote the growth of granulation tissue.